Neurobiology of Kratom and its main alkaloid mitragynine
Kappa Opioid Receptor Structure Revealed, A Potential Milestone in Medication Development | National Institute on Drug Abuse (NIDA)
Kratom | National Institute on Drug Abuse (NIDA)
7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects | ACS Central Science
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions | Scientific Reports
Opioid-based plant might not be best solution for those seeking to curb habitual alcohol use - Purdue University News
Central nervous system receptor binding data for mitragynine.... | Download Table
A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects | Journal of Medicinal Chemistry
Medicines | Free Full-Text | Mitragyna speciosa: Clinical, Toxicological Aspects and Analysis in Biological and Non-Biological Samples
Scientists Just Solved a Major Piece of the Opioid Puzzle | WIRED
Frontiers | Evaluation of Kratom Opioid Derivatives as Potential Treatment Option for Alcohol Use Disorder
Frontiers | Kratom Use Within the Context of the Evolving Opioid Crisis and the COVID-19 Pandemic in the United States
Pharmaceutics | Free Full-Text | Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
The effects of kratom on restraint–stress-induced analgesia and its mechanisms of action - ScienceDirect
Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse | National Institute on Drug Abuse (NIDA)
Molecules | Free Full-Text | Biased Opioid Ligands
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions | Scientific Reports
Site selective C–H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy | Nature Communications
Simulated Side Effects: FDA Uses Novel Computer Model to Guide Kratom Policy | Bill of Health
Pharmaceuticals | Free Full-Text | Pharmacokinetics and Pharmacodynamics of Salvinorin A and Salvia divinorum: Clinical and Forensic Aspects
